The activation of phospholipase D (PLD) produces phosphatidic acid (PA), whereas plant sphingosine kinase (SPHK) phosphorylates long-chain bases to generate long-chain base-1-phosphates such as phytosphingosine-1-phosphate (phyto-S1P). PA and phyto-S1P have been identified as lipid messengers. Recent studies have shown that PA interacts directly with SPHKs in Arabidopsis, and that the interaction promotes SPHK activity. However, SPHK and phyto-S1P act upstream of PLDα1 and PA in the stomatal response to abscisic acid (ABA). These findings indicate that SPHK/phyto-S1P and PLD/PA are co-dependent in the amplification of lipid messengers, and that crosstalk between the sphingolipid- and phospholipid-mediated signaling pathways may play important roles in plant stress signaling.
Keywords: phospholipase D, phosphatidic acid, sphingosine kinase, phytosphingosine, lipid signaling, abscisic acid
Citation: Guo L and Wang X (2012) Crosstalk between phospholipase D and sphingosine kinase in plant stress signaling. Front. Plant Sci. 3:51. doi: 10.3389/fpls.2012.00051
Received: 13 December 2011; Accepted: 28 February 2012;
Published online: 19 March 2012.
Edited by:Kent D. Chapman, University of North Texas, USA
Reviewed by:Edgar B. Cahoon, University of Nebraska, USA
Copyright: © 2012 Guo and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License, which permits non-commercial use, distribution, and reproduction in other forums, provided the original authors and source are credited.
*Correspondence: Xuemin Wang, Department of Biology, University of Missouri, St. Louis, MO 63121, USA. e-mail: firstname.lastname@example.org