@ARTICLE{10.3389/fimmu.2014.00098, AUTHOR={Danger, Richard and Braza, Faouzi and Giral, Magali and Soulillou, Jean-Paul and Brouard, Sophie}, TITLE={MicroRNAs, Major Players in B Cells Homeostasis and Function}, JOURNAL={Frontiers in Immunology}, VOLUME={5}, YEAR={2014}, URL={https://www.frontiersin.org/articles/10.3389/fimmu.2014.00098}, DOI={10.3389/fimmu.2014.00098}, ISSN={1664-3224}, ABSTRACT={As a main actor in humoral immunity, B cells participate in various antibody-related disorders. However, a deeper understanding of B-cell differentiation and function is needed in order to decipher their immune-modulatory roles, notably with the recent highlighting of regulatory B cells. microRNAs (miRNAs), key factors in various biological and pathological processes, have been shown to be essential for B-cell homeostasis, and therefore understanding their participation in B-cell biology could help identify biomarkers and contribute toward curing B-cell-related immune disorders. This review aims to report studies casting light on the roles played by miRNAs in B-cell lineage and function and B-cell-related immune pathologies.} }