4
Impact Factor
This article is part of the Research Topic Human health and disease in a microbial world

Review ARTICLE

Front. Microbiol., 30 May 2011 | http://dx.doi.org/10.3389/fmicb.2011.00093

Environmental and gut Bacteroidetes: the food connection

François Thomas1,2, Jan-Hendrik Hehemann1,2, Etienne Rebuffet1,2, Mirjam Czjzek1,2 and Gurvan Michel1,2*
  • 1 UMR 7139, Marine Plants and Biomolecules, Station Biologique de Roscoff, UPMC University, Paris 6, Roscoff, France
  • 2 UMR 7139, Marine Plants and Biomolecules, Station Biologique de Roscoff, CNRS, Roscoff, France

Members of the diverse bacterial phylum Bacteroidetes have colonized virtually all types of habitats on Earth. They are among the major members of the microbiota of animals, especially in the gastrointestinal tract, can act as pathogens and are frequently found in soils, oceans and freshwater. In these contrasting ecological niches, Bacteroidetes are increasingly regarded as specialists for the degradation of high molecular weight organic matter, i.e., proteins and carbohydrates. This review presents the current knowledge on the role and mechanisms of polysaccharide degradation by Bacteroidetes in their respective habitats. The recent sequencing of Bacteroidetes genomes confirms the presence of numerous carbohydrate-active enzymes covering a large spectrum of substrates from plant, algal, and animal origin. Comparative genomics reveal specific Polysaccharide Utilization Loci shared between distantly related members of the phylum, either in environmental or gut-associated species. Moreover, Bacteroidetes genomes appear to be highly plastic and frequently reorganized through genetic rearrangements, gene duplications and lateral gene transfers (LGT), a feature that could have driven their adaptation to distinct ecological niches. Evidence is accumulating that the nature of the diet shapes the composition of the intestinal microbiota. We address the potential links between gut and environmental bacteria through food consumption. LGT can provide gut bacteria with original sets of utensils to degrade otherwise refractory substrates found in the diet. A more complete understanding of the genetic gateways between food-associated environmental species and intestinal microbial communities sheds new light on the origin and evolution of Bacteroidetes as animals’ symbionts. It also raises the question as to how the consumption of increasingly hygienic and processed food deprives our microbiota from useful environmental genes and possibly affects our health.

Keywords: Bacteroidetes, adaptation to environmental niches, microbiota

Citation: Thomas F, Hehemann J-H, Rebuffet E, Czjzek M and Michel G (2011) Environmental and gut Bacteroidetes: the food connection. Front. Microbio. 2:93. doi: 10.3389/fmicb.2011.00093

Received: 12 January 2011; Accepted: 14 April 2011;
Published online: 30 May 2011.

Edited by:

Peter J. Turnbaugh, Harvard University, USA

Reviewed by:

Deborah Threadgill, North Carolina State University, USA
Alain Stintzi, Ottawa Institute of Systems Biology, Canada

Copyright: © 2011 Thomas, Hehemann, Rebuffet, Czjzek and Michel. This is an open-access article subject to a non-exclusive license between the authors and Frontiers Media SA, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and other Frontiers conditions are complied with.

*Correspondence: Gurvan Michel, UMR 7139, CNRS/UPMC, Marine Plants and Biomolecules, Station Biologique de Roscoff, Place Georges Teissier, 29680 Roscoff, France. e-mail: gurvan@sb-roscoff.fr