@ARTICLE{10.3389/fmicb.2014.00226, AUTHOR={Saraya, Takeshi and Kurai, Daisuke and Ishii, Haruyuki and Ito, Anri and Sasaki, Yoshiko and Niwa, Shoichi and Kiyota, Naoko and Tsukagoshi, Hiroyuki and Kozawa, Kunihisa and Goto, Hajime and Takizawa, Hajime}, TITLE={Epidemiology of virus-induced asthma exacerbations: with special reference to the role of human rhinovirus}, JOURNAL={Frontiers in Microbiology}, VOLUME={5}, YEAR={2014}, URL={https://www.frontiersin.org/articles/10.3389/fmicb.2014.00226}, DOI={10.3389/fmicb.2014.00226}, ISSN={1664-302X}, ABSTRACT={Viral respiratory infections may be associated with the virus-induced asthma in adults as well as children. Particularly, human rhinovirus is strongly suggested a major candidate for the associations of the virus-induced asthma. Thus, in this review, we reviewed and focused on the epidemiology, pathophysiology, and treatment of virus-induced asthma with special reference on human rhinovirus. Furthermore, we added our preliminary data regarding the clinical and virological findings in the present review.} }