%A Grønli,Janne %A Soule,Jonathan %A Bramham,Clive %D 2014 %J Frontiers in Behavioral Neuroscience %C %F %G English %K Sleep,synaptic plasticity,Long-Term Potentiation,stress,mood,Depression,Gene Expression,protein synthesis,Translation control,Brain-Derived Neurotrophic Factor,activity-regulated cytoskeleton-associated protein,REM sleep,Arc %Q %R 10.3389/fnbeh.2013.00224 %W %L %M %P %7 %8 2014-January-21 %9 Review %+ Prof Clive Bramham,University of Bergen,Department of Biomedicine and KB Jebsen Centre for Research on Neuropsychiatric Disorders,Jonas Lies vei 91,Bergen,5009,Norway,clive.bramham@biomed.uib.no %# %! Sleep, synaptic plasticity, and the impact of stress %* %< %T Sleep and protein synthesis-dependent synaptic plasticity: impacts of sleep loss and stress %U https://www.frontiersin.org/articles/10.3389/fnbeh.2013.00224 %V 7 %0 JOURNAL ARTICLE %@ 1662-5153 %X Sleep has been ascribed a critical role in cognitive functioning. Several lines of evidence implicate sleep in the consolidation of synaptic plasticity and long-term memory. Stress disrupts sleep while impairing synaptic plasticity and cognitive performance. Here, we discuss evidence linking sleep to mechanisms of protein synthesis-dependent synaptic plasticity and synaptic scaling. We then consider how disruption of sleep by acute and chronic stress may impair these mechanisms and degrade sleep function.