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Impact Factor

Original Research ARTICLE

Front. Hum. Neurosci., 26 February 2013 | http://dx.doi.org/10.3389/fnhum.2013.00047

Differential auditory-oculomotor interactions in patients with right vs. left sided subjective tinnitus: a saccade study

Alexandre Lang1*, Marine Vernet1, Qing Yang1, Christophe Orssaud2, Alain Londero3 and Zoï Kapoula1
  • 1CNRS CESEM - UMR 8194, Université Paris Descartes, Paris, France
  • 2Service d'Ophtalmologie, Hôpital Européen Georges Pompidou, Paris, France
  • 3Service d'ORL et de Chirurgie Cervico-Faciale, Hôpital Européen Georges Pompidou, Paris, France

Subjective tinnitus (ST) is a frequent but poorly understood medical condition. Recent studies demonstrated abnormalities in several types of eye movements (smooth pursuit, optokinetic nystagmus, fixation, and vergence) in ST patients. The present study investigates horizontal and vertical saccades in patients with tinnitus lateralized predominantly to the left or to the right side. Compared to left sided ST, tinnitus perceived on the right side impaired almost all the parameters of saccades (latency, amplitude, velocity, etc.) and noticeably the upward saccades. Relative to controls, saccades from both groups were more dysmetric and were characterized by increased saccade disconjugacy (i.e., poor binocular coordination). Although the precise mechanisms linking ST and saccadic control remain unexplained, these data suggest that ST can lead to detrimental auditory, visuomotor, and perhaps vestibular interactions.

Keywords: asymmetry, cross-modal, interactions, tinnitus, visually guided saccades

Citation: Lang A, Vernet M, Yang Q, Orssaud C, Londero A and Kapoula Z (2013) Differential auditory-oculomotor interactions in patients with right vs. left sided subjective tinnitus: a saccade study. Front. Hum. Neurosci. 7:47. doi: 10.3389/fnhum.2013.00047

Received: 23 November 2012; Accepted: 05 February 2013;
Published online: 26 February 2013.

Edited by:

John J. Foxe, Albert Einstein College of Medicine, USA

Reviewed by:

Hans Colonius, Carl von Ossietzky Universität Oldenburg, Germany
Mark R. Harwood, City College of New York, USA

Copyright © 2013 Lang, Vernet, Yang, Orssaud, Londero and Kapoula. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc.

*Correspondence: Alexandre Lang, CESEM - UMR 8194, Université Paris V, 45 rue des Saints-Pères, 75270 Paris Cedex 06, France. e-mail: lang.alexandre@gmail.com