TY - JOUR AU - Lawson, Rebecca P. AU - Rees, Geraint AU - Friston, Karl J. PY - 2014 M3 - Hypothesis and Theory TI - An aberrant precision account of autism JO - Frontiers in Human Neuroscience UR - https://www.frontiersin.org/articles/10.3389/fnhum.2014.00302 VL - 8 SN - 1662-5161 N2 - Autism is a neurodevelopmental disorder characterized by problems with social-communication, restricted interests and repetitive behavior. A recent and thought-provoking article presented a normative explanation for the perceptual symptoms of autism in terms of a failure of Bayesian inference (Pellicano and Burr, 2012). In response, we suggested that when Bayesian inference is grounded in its neural instantiation—namely, predictive coding—many features of autistic perception can be attributed to aberrant precision (or beliefs about precision) within the context of hierarchical message passing in the brain (Friston et al., 2013). Here, we unpack the aberrant precision account of autism. Specifically, we consider how empirical findings—that speak directly or indirectly to neurobiological mechanisms—are consistent with the aberrant encoding of precision in autism; in particular, an imbalance of the precision ascribed to sensory evidence relative to prior beliefs. ER -