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ORIGINAL RESEARCH article

Front. Pharmacol., 28 January 2016
Sec. Pharmacology of Anti-Cancer Drugs

Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells

\r\nNima Samie,*Nima Samie1,2*Batoul Sadat HaerianBatoul Sadat Haerian1Sekaran Muniandy*Sekaran Muniandy3*Anita MarlinaAnita Marlina4M. S. Kanthimathi,M. S. Kanthimathi3,5Norbani B. AbdullahNorbani B. Abdullah4Gholamreza AhmadianGholamreza Ahmadian6Raja E. R. AziddinRaja E. R. Aziddin2
  • 1Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 2Drug and Research Unit, Department of Pathology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia
  • 3Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
  • 4Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia
  • 5Faculty of Medicine, University of Malaya Centre for Proteomics Research, University of Malaya, Kuala Lumpur, Malaysia
  • 6Department of Environmental and Industrial Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran

Citation: Samie N, Haerian BS, Muniandy S, Marlina A, Kanthimathi MS, Abdullah NB, Ahmadian G and Aziddin RER (2016) Mechanism of Action of the Novel Nickel(II) Complex in Simultaneous Reactivation of the Apoptotic Signaling Networks Against Human Colon Cancer Cells. Front. Pharmacol. 6:313. doi: 10.3389/fphar.2015.00313

Received: 19 November 2015; Accepted: 18 December 2015;
Published: 28 January 2016; Retracted: 29 June 2016.

Edited by:

Olivier Cuvillier, Centre National de la Recherche Scientifique, France

Reviewed by:

Stefania Nobili, University of Florence, Italy
Maryna Van De Venter, Nelson Mandela Metropolitan University, South Africa

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