%A Indriolo,Emily %A Goring,Daphne R. %D 2014 %J Frontiers in Plant Science %C %F %G English %K Ubiquitination,Cell signaling,self-incompatibility,Arabidopsis,Brassicaceae %Q %R 10.3389/fpls.2014.00181 %W %L %M %P %7 %8 2014-May-05 %9 Mini Review %+ Prof Daphne R. Goring,Centre for the Analysis of Genome Evolution & Function, University of Toronto,Toronto, ON, Canada,d.goring@utoronto.ca %+ Prof Daphne R. Goring,Department of Cell & Systems Biology, University of Toronto,Toronto, ON, Canada,d.goring@utoronto.ca %# %! ARC1’s role in self-pollen rejection %* %< %T A conserved role for the ARC1 E3 ligase in Brassicaceae self-incompatibility %U https://www.frontiersin.org/articles/10.3389/fpls.2014.00181 %V 5 %0 JOURNAL ARTICLE %@ 1664-462X %X Ubiquitination plays essential roles in the regulation of many processes in plants including pollen rejection in self-incompatible species. In the Brassicaceae (mustard family), self-incompatibility drives the rejection of self-pollen by preventing pollen hydration following pollen contact with the stigmatic surface. Self-pollen is recognized by a ligand-receptor pair: the pollen S-locus cysteine rich/S-locus protein 11 (SCR/SP11) ligand and the pistil S receptor kinase (SRK). Following self-pollen contact, the SCR/SP11 ligand on the pollen surface binds to SRK on the pistil surface, and the SRK-activated signaling pathway is initiated. This pathway includes the armadillo repeat containing 1 (ARC1) protein, a member of the plant U-box (PUB) family of E3 ubiquitin ligases. ARC1 is a functional E3 ligase and is required downstream of SRK for the self-incompatibility response. This mini review highlights our recent progress in establishing ARC1’s conserved role in self-pollen rejection in Brassica and Arabidopsis species and discusses future research directions in this field.