Original Research ARTICLE

Front. Public Health, 21 August 2014 | http://dx.doi.org/10.3389/fpubh.2014.00115

Synthetic biology and biosecurity: challenging the “myths”

imageCatherine Jefferson, imageFilippa Lentzos and imageClaire Marris*
  • Department of Social Science, Health and Medicine, King’s College London, London, UK

Synthetic biology, a field that aims to “make biology easier to engineer,” is routinely described as leading to an increase in the “dual-use” threat, i.e., the potential for the same scientific research to be “used” for peaceful purposes or “misused” for warfare or terrorism. Fears have been expressed that the “de-skilling” of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five “myths” that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these “myths” play an important role in defining synthetic biology as a “promissory” field of research and as an “emerging technology” in need of governance.

Keywords: synthetic biology, biosecurity, bioterrorism, biological weapons, DIY biology, iGEM, policy discourse, non-proliferation

Citation: Jefferson C, Lentzos F and Marris C (2014) Synthetic biology and biosecurity: challenging the “myths”. Front. Public Health 2:115. doi: 10.3389/fpubh.2014.00115

Received: 11 May 2014; Accepted: 23 July 2014;
Published online: 21 August 2014.

Edited by:

Kathleen Vogel, Cornell University, USA

Reviewed by:

Kathleen Vogel, Cornell University, USA
Luis Campos, University of New Mexico, USA

Copyright: © 2014 Jefferson, Lentzos and Marris. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Claire Marris, Department of Social Science, Health and Medicine, King’s College London, Strand, London WC2R 2LS, UK e-mail: claire.marris@kcl.ac.uk