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Focused Review ARTICLE

Front. Neurosci., 15 September 2009 | http://dx.doi.org/10.3389/neuro.01.027.2009

Hebbian reverberations in emotional memory micro circuits

1
Department of Psychiatry and Program in Neuroscience, USU, Bethesda, MD, USA
2
Center for Neural Science, NYU, New York, NY, USA
3
NAMC, CNRS-UMR8620, Université Paris-Sud, Orsay, France
The study of memory in most behavioral paradigms, including emotional memory paradigms, has focused on the feed forward components that underlie Hebb's first postulate, associative synaptic plasticity. Hebb's second postulate argues that activated ensembles of neurons reverberate in order to provide temporal coordination of different neural signals, and thereby facilitate coincidence detection. Recent evidence from our groups has suggested that the lateral amygdala (LA) contains recurrent microcircuits and that these may reverberate. Additionally this reverberant activity is precisely timed with latencies that would facilitate coincidence detection between cortical and sub cortical afferents to the LA. Thus, recent data at the microcircuit level in the amygdala provide some physiological evidence in support of the second Hebbian postulate.
Keywords:
amygdala, fear, ensembles, network, recurrent
Citation:
Johnson LR, LeDoux J and Doyere V (2009). Hebbian Reverberations in Emotional Memory Micro Circuits.Front. Neurosci. 3,2:198- 205. doi: 10.3389/neuro.01.027.2009
Received:
09 May 2009;
 Paper pending published:
26 June 2009;
Accepted:
09 July 2009;
 Published online:
15 September 2009.

Edited by:

Gilles Laurent, California Institute of Technology, USA

Reviewed by:

Shreesh P. Mysore, Stanford University, USA
Copyright:
© 2009 Johnson, LeDoux and Doyère. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
*Correspondence:
Luke R Johnson PhD Department of Psychiatry and Program in Neuroscience Uniformed Services University, Bethesda, MD, 20814. email: Luke.Johnson@usuhs.mil