AUTHOR=Liu Zhaoqi , Zhang Shihua 

TITLE=Toward a systematic understanding of cancers: a survey of the pan-cancer study

JOURNAL=Frontiers in Genetics

VOLUME=5

YEAR=2014

URL=https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2014.00194

DOI=10.3389/fgene.2014.00194

ISSN=1664-8021

ABSTRACT=<p>Studies on molecular aberrations of cancer patients have increased unprecedentedly in scale and accessibility, allowing large-scale integrative cross-cancer analysis. Pan-cancer study is becoming a valuable paradigm for cancer genomics. Here, we review recent advances in this field and highlight the potential challenges and directions especially from the computational angle.</p>