AUTHOR=Geneugelijk Kirsten , Niemann Matthias , Drylewicz Julia , van Zuilen Arjan D. , Joosten Irma , Allebes Wil A. , van der Meer Arnold , Hilbrands Luuk B. , Baas Marije C. , Hack C. Erik , van Reekum Franka E. , Verhaar Marianne C. , Kamburova Elena G. , Bots Michiel L. , Seelen Marc A. J. , Sanders Jan Stephan , Hepkema Bouke G. , Lambeck Annechien J. , Bungener Laura B. , Roozendaal Caroline , Tilanus Marcel G. J. , Vanderlocht Joris , Voorter Christien E. , Wieten Lotte , van Duijnhoven Elly M. , Gelens Mariëlle , Christiaans Maarten H. L. , van Ittersum Frans J. , Nurmohamed Azam , Lardy Junior N. M. , Swelsen Wendy , van der Pant Karlijn A. , van der Weerd Neelke C. , ten Berge Ineke J. M. , Bemelman Fréderike J. , Hoitsma Andries , van der Boog Paul J. M. , de Fijter Johan W. , Betjes Michiel G. H. , Heidt Sebastiaan , Roelen Dave L. , Claas Frans H. , Otten Henny G. , Spierings Eric TITLE=PIRCHE-II Is Related to Graft Failure after Kidney Transplantation JOURNAL=Frontiers in Immunology VOLUME=9 YEAR=2018 URL=https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00321 DOI=10.3389/fimmu.2018.00321 ISSN=1664-3224 ABSTRACT=
Individual HLA mismatches may differentially impact graft survival after kidney transplantation. Therefore, there is a need for a reliable tool to define permissible HLA mismatches in kidney transplantation. We previously demonstrated that donor-derived Predicted Indirectly ReCognizable HLA Epitopes presented by recipient HLA class II (PIRCHE-II) play a role in