AUTHOR=Chistiakov Dimitry A. , Bobryshev Yuri V. , Kozarov Emil , Sobenin Igor A. , Orekhov Alexander N. 

TITLE=Intestinal mucosal tolerance and impact of gut microbiota to mucosal tolerance

JOURNAL=Frontiers in Microbiology

VOLUME=5

YEAR=2015

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2014.00781

DOI=10.3389/fmicb.2014.00781

ISSN=1664-302X

ABSTRACT=<p>The mucosal barriers are very sensitive to pathogenic infection, thereby assuming the capacity of the mucosal immune system to induce protective immunity to harmful antigens and tolerance against harmless substances. This review provides current information about mechanisms of induction of mucosal tolerance and about impact of gut microbiota to mucosal tolerance.</p>