AUTHOR=Tadra-Sfeir Michelle Z. , Faoro Helisson , Camilios-Neto Doumit , Brusamarello-Santos Liziane , Balsanelli Eduardo , Weiss Vinicius , Baura Valter A. , Wassem Roseli , Cruz Leonardo M. , De Oliveira Pedrosa Fábio , Souza Emanuel M. , Monteiro Rose A. 

TITLE=Genome wide transcriptional profiling of Herbaspirillum seropedicae SmR1 grown in the presence of naringenin

JOURNAL=Frontiers in Microbiology

VOLUME=6

YEAR=2015

URL=https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2015.00491

DOI=10.3389/fmicb.2015.00491

ISSN=1664-302X

ABSTRACT=<p><italic>Herbaspirillum seropedicae</italic> is a diazotrophic bacterium which associates endophytically with economically important <italic>gramineae</italic>. Flavonoids such as naringenin have been shown to have an effect on the interaction between <italic>H. seropedicae</italic> and its host plants. We used a high-throughput sequencing based method (RNA-Seq) to access the influence of naringenin on the whole transcriptome profile of <italic>H. seropedicae.</italic> Three hundred and four genes were downregulated and seventy seven were upregulated by naringenin. Data analysis revealed that genes related to bacterial flagella biosynthesis, chemotaxis and biosynthesis of peptidoglycan were repressed by naringenin. Moreover, genes involved in aromatic metabolism and multidrug transport efllux were actived.</p>