AUTHOR=Meador Kimford , Gedzelman Evan TITLE=Neurological and Psychiatric Sequelae of Developmental Exposure to Antiepileptic Drugs JOURNAL=Frontiers in Neurology VOLUME=3 YEAR=2012 URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2012.00182 DOI=10.3389/fneur.2012.00182 ISSN=1664-2295 ABSTRACT=

The neurons in the developing mammalian brain are susceptible to antiepileptic drug (AED) effects. It is known that later in life deficits in cognitive performance as well as psychiatric deficits can manifest after early AED exposure. The extent of these deficits will be addressed. This review will attempt to draw parallels between the existent animal models and human studies. Through analysis of these studies, important future research will be elucidated and possible new and emerging therapies will be discussed.