AUTHOR=Gil-Gouveia Raquel , Pinto Joana , Figueiredo Patricia , Vilela Pedro Ferro , Martins Isabel Pavão 

TITLE=An Arterial Spin Labeling MRI Perfusion Study of Migraine without Aura Attacks

JOURNAL=Frontiers in Neurology

VOLUME=8

YEAR=2017

URL=https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2017.00280

DOI=10.3389/fneur.2017.00280

ISSN=1664-2295

ABSTRACT=<sec id="ST1"><title>Background</title><p>Studies of brain perfusion during migraine without aura attacks have inconsistent results.</p></sec><sec id="ST2"><title>Methods</title><p>Arterial spin labeling MRI, a non-invasive quantitative perfusion technique, was used to prospectively study a spontaneous untreated migraine without aura attack and a headache-free period. Image analysis used FSL and MATLAB software; Group analysis used permutation methods for perfusion differences between sessions.</p></sec><sec id="ST3"><title>Results</title><p>Thirteen women (age 35.7) were scanned during an attack of an average intensity of 6.8 (on 0–10 Visual Analog Scale) and 16 h duration. No global or regional perfusion differences were identified when comparing migraine and migraine-free sessions.</p></sec><sec id="ST4"><title>Discussion</title><p>Our findings suggest that the painful phase of migraine without aura attacks is not associated with brain perfusion abnormalities.</p></sec>