AUTHOR=Kim Linda H. , Sharma Sandeep , Sharples Simon A. , Mayr Kyle A. , Kwok Charlie H. T. , Whelan Patrick J. 

TITLE=Integration of Descending Command Systems for the Generation of Context-Specific Locomotor Behaviors

JOURNAL=Frontiers in Neuroscience

VOLUME=11

YEAR=2017

URL=https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2017.00581

DOI=10.3389/fnins.2017.00581

ISSN=1662-453X

ABSTRACT=<p>Over the past decade there has been a renaissance in our understanding of spinal cord circuits; new technologies are beginning to provide key insights into descending circuits which project onto spinal cord central pattern generators. By integrating work from both the locomotor and animal behavioral fields, we can now examine context-specific control of locomotion, with an emphasis on descending modulation arising from various regions of the brainstem. Here we examine approach and avoidance behaviors and the circuits that lead to the production and arrest of locomotion.</p>