AUTHOR=Khoomrung Sakda , Wanichthanarak Kwanjeera , Nookaew Intawat , Thamsermsang Onusa , Seubnooch Patcharamon , Laohapand Tawee , Akarasereenont Pravit TITLE=Metabolomics and Integrative Omics for the Development of Thai Traditional Medicine JOURNAL=Frontiers in Pharmacology VOLUME=8 YEAR=2017 URL=https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00474 DOI=10.3389/fphar.2017.00474 ISSN=1663-9812 ABSTRACT=

In recent years, interest in studies of traditional medicine in Asian and African countries has gradually increased due to its potential to complement modern medicine. In this review, we provide an overview of Thai traditional medicine (TTM) current development, and ongoing research activities of TTM related to metabolomics. This review will also focus on three important elements of systems biology analysis of TTM including analytical techniques, statistical approaches and bioinformatics tools for handling and analyzing untargeted metabolomics data. The main objective of this data analysis is to gain a comprehensive understanding of the system wide effects that TTM has on individuals. Furthermore, potential applications of metabolomics and systems medicine in TTM will also be discussed.