Monoamine neurotransmitters such as dopamine, noradrenaline, histamine and serotonin play a central role in the pathophysiology of major neuropsychiatric illnesses, such as anxiety and mood disorders, schizophrenia, autism-spectrum disorders, Parkinson’s disease, epilepsy, and dementias. The aim of this Research Topic is to highlight interdisciplinary research using drug design, data-mining, structure-based drug design, medicinal chemistry and biological investigation in vitro and in vivo disease models, with input from behavioral and genetic studies. In this issue we encourage submissions of basic and/or clinical studies and review papers that summarize current knowledge and point out important deficiencies in our current understanding of the important monoamines systems.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
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